Aurogra 100 Mg

Aurogra 100 mg is a pharmaceutical drug with Sildenafil Citrate as an active ingredient, which is used to treat erectile dysfunction in men. It is a generic form of Viagra with the same active ingredient, Sildenafil Phosphodiesterase Type 5 (PDE5) inhibitor that acts by increasing blood flow to the penis and aiding men in achieving and maintaining an erection.

Aurogra 100 mg relaxes blood vessels as Sildenafil Citrate inhibits the phosphodiesterase type 5 enzyme that regulates the blood flow. It enhances blood flow to the penis, which enables a natural response to sexual stimulation, helping men achieve and maintain erections.

• PDE5 inhibition: Aurogra 100mg includes Sildenafil Citrate, which selectively inhibits phosphodiesterase type 5 (PDE5) enzyme.
• Increased cGMP levels: PDE5 inhibition results in elevated levels of cyclic guanosine monophosphate (cGMP) in the penis.
• Smooth muscle relaxation: cGMP induces smooth muscle relaxation, enabling the blood vessels to dilate.
• Increased blood flow: Vascular dilation increases blood flow to the penis, facilitating an erection.

Dosage

• 1 (100 mg) Tablet can be taken orally, 1 hour before sexual activity.
• Do not exceed more than 1 tablet dosage in a day.
• Take the tablet on an empty stomach or with a light meal for optimal absorption.

Side Effects:

• Headache
• Facial flushing
• Dizziness
• Indigestion
• Nasal congestion
• Blue-tinged vision
• Muscle pain

Rare but serious side effects may include:

• Priapism (long-lasting erection)
• Sudden blindness
• Sudden hearing impairment
• Allergic reactions

Pharmacokinetics

• Absorption: Sildenafil Citrate is absorbed quickly, with the maximum plasma concentrations attained within 30-120 minutes.
• Metabolism: Aurogra 100mg is metabolized in the liver and has a half-life of about 3-4 hours.
• Excretion: The metabolites are excreted through feces and urine.

Aurogra 100 mg interactions are classified into several categories:

• Drug interactions
• Food interactions
• Disease interactions

• Nitrates: Contradicted because of the potential for severe hypotension (e.g., nitroglycerin, isosorbide dinitrate)
• Alpha-blockers: Can cause symptomatic hypotension (e.g., doxazosin, terazosin)
• Antihypertensives: Can increase the hypotensive effects (e.g., beta-blockers, calcium channel blockers)
• Protease inhibitors: Can raise sildenafil levels (e.g., ritonavir, saquinavir)
• Antibiotics: Can raise sildenafil levels (e.g., erythromycin, clarithromycin)

Food Interaction

• Grapefruit juice: Can raise sildenafil levels
• Alcohol: Can enhance the chances of side effects such as dizziness and hypotension

Other Interactions

• Other ED medications
• Must not be used with Aurogra without the advice of a healthcare provider
• Certain medical conditions: Patients with heart disease, high blood pressure, or other disorders must consult a healthcare provider before using Aurogra

Disease Interactions

• Cardiovascular Conditions: Patients with advanced heart disease, recent myocardial infarction, or uncontrolled hypertension must get in touch with their physician prior to using Aurogra.
• Hepatic Impairment: Patients with liver failure might need dosage adjustment, as Aurogra is metabolized through the liver.
• Renal Impairment: Patients with kidney dysfunction can also need dose adjustments since Aurogra is eliminated by the kidneys.

The efficacy and safety of Aurogra have been studied in numerous clinical trials. These trials have confirmed that sildenafil citrate, the drug in Aurogra, greatly enhances erectile function in men with ED. In a trial, more than 80% of men showed enhanced erectile response following sildenafil treatment versus placebo.

 Precautions

• Aurogra 100mg is to be administered cautiously in patients with cardiovascular conditions.
• Aurogra 100mg is not to be administered to patients consuming nitrates.
• Patients with risk factors for priapism are to be administered Aurogra 100mg cautiously.
• Usually administered an hour prior to expected sexual activity, with a maximum rate of once daily.
• Use is contraindicated in women, children, and adolescents because of the lack of research.

Conclusion

Aurogra 100mg is a medically tested medication to treat erectile dysfunction and pulmonary arterial hypertension with efficacy and safety under medical guidance. It is necessary to consult a doctor prior to taking the medicine in order to get the best results with minimal risks.

References

https://pmc.ncbi.nlm.nih.gov/articles/PMC4623654/

https://pmc.ncbi.nlm.nih.gov/articles/PMC9303470/

https://pmc.ncbi.nlm.nih.gov/articles/PMC11970765/

FAQs

1.) What is Aurogra 100mg used for?

Aurogra 100mg is utilized to treat erectile dysfunction (ED) in males.

2) How does Aurogra 100mg function?

Aurogra 100mg functions by inhibiting PDE5, enhancing blood flow to the penis, and facilitating an erection.

3) What are the common side effects?

Popular side effects are headache, facial flushing, dizziness, indigestion, and nasal congestion.

4) Can Aurogra 100mg be combined with other drugs?

Aurogra 100mg can interact with some drugs, i.e., nitrates and alpha-blockers. Refer to a health professional before use.

5) Aurogra 100mg safe for all?

Aurogra 100mg is not for everyone, especially those with certain medical conditions or on certain drugs. Talk to a physician before using it.

6) What is the recommended dosage of Aurogra?

The recommended dosage is 50 mg, but it can be adjusted to 25 mg or 100 mg based on the individual.