Ocupol is an antibiotic ointment for the eyes consisting of Polymyxin B Sulphate and Bacitracin Zinc. It’s indicated to treat infections of the eye caused by bacteria, e.g.,conjunctivitis or blepharitis

Key Features

How does Ocupol 5 gm work?

Ocupol ointment accomplishes this by preventing bacteria that cause eye infections from growing. Polymyxin B Sulphate and Bacitracin Zinc are two antibiotics that combine in killing a broad range of bacteria.

• Bacteria killing: Polymyxin B Sulphate and Bacitracin Zinc combine to destroy a broad spectrum of bacteria that infect the eyes.
• Bacterial growth inhibition: The antibiotics in Ocupol ointment prevent the growth of bacteria by inhibiting their cell wall development and protein synthesis.
• Infection reduction: Ocupol ointment kills bacteria and stops their growth, thus reducing the infection and inflammation of the eye.

Mechanism of action of Ocupol ointment includes

• Bacterial cell membrane disruption: Polymyxin B Sulphate breaks the cell membrane of the bacteria, killing them.
• Protein synthesis inhibition: Bacitracin Zinc stops the synthesis of proteins that are necessary for bacterial growth and survival.

Usage

Ocupol ointment is applied for the treatment of bacterial infections of the eye. To achieve the best therapeutic results, it is necessary to adhere to the prescribed dosage and usage guidelines.

• Eye bacterial infections: Ocupol 5 gm is employed in the treatment of bacterial eye infections, including conjunctivitis, blepharitis and other eye infections.
• Pre-operative and post-operative treatments: It can be employed for preventing or treating infection in eye surgery patients.

Dosage

The indicated dosage is to put a tiny amount of ointment in the eye(s) affected 2-4 times daily or as directed by your physician.

Side Effects

• Eye irritation
• Redness
• Itching
• Burning sensation

Pharmacokinetics

• Local action: Ocupol 5 gm has a local action in the eye with minimal systemic absorption.
• Limited distribution: The Ocupol 5 gm contains antibiotics that are mainly distributed to the ocular tissues, with limited distribution to the rest of the body.
• Minimal metabolism: The antibiotics in Ocupol 5 gm are not substantially metabolized systemically.

Interactions

• Other eye medications: Ocupol 5 gm can interact with other eye medications such as other antibiotics, antivirals, and corticosteroids.
• Muscle relaxants: Ocupol 5 gm may potentiate the action of muscle relaxants.
• Neuromuscular blocking agents: Ocupol 5 gm can potentiate the action of neuromuscular blocking agents.
• Other antibiotics: Ocupol 5 gm can interact with other antibiotics, such as aminoglycosides, thereby enhancing the potential for nephrotoxicity and ototoxicity.

Precautions

• Using the drug as directed by your physician.
• Not coming into contact with the tip of the tube with any surface so as to minimize contamination.
• Wearing contact lenses only where advised by your doctor.
• Monitoring for infection signs or worsening symptoms.

Conclusion

Ocupol 5 gm is antibiotic ointment combined to be employed to cure eye infections caused by bacteria. It may be effective but must be used with the advice of a healthcare practitioner and in accordance with the prescribed dosage and protection.

FAQ’s

1) What is Ocupol ointment prescribed for?
Ocupol ointment is prescribed to cure eye infections caused by bacteria, like conjunctivitis or blepharitis

2) How does Ocupol Ointment work?
Ocupol ointment accomplishes this by preventing bacteria that cause eye infections from growing.

3) How long does it take for Ocupol ointment to start working?
The action of Ocupol ointment begins within a few days of treatment.

4) Should I wear contact lenses when using Ocupol ointment?
Wear contact lenses only if advised by your doctor.

5) Is Ocupol safe?
Yes, generally it is safe but it is recommended to use after consulting medical professional or Ophthalmologist.

References

• https://www.ncbi.nlm.nih.gov/books/NBK536993/
• https://pmc.ncbi.nlm.nih.gov/articles/PMC1324633/